Academy of Mathematics and Systems Science, CAS
Colloquia & Seminars

Speaker:	Dr.Louxin Zhang，Department of Mathematics ,National University of Singapore
Inviter:	王勇研究员
Title:	Benchmarking Computational Methods for Prediction of Drug Responses
Time & Venue:	2019.12.19 9:30 N205
Abstract:	Drug response prediction arises from both basic and clinical research of personalized therapy, as well as drug discovery for cancers. With gene expression profiles and other omics data being available for over 1000 cancer cell lines and tissues, different machine learning approaches have been applied to drug response prediction. These methods appear in a body of literature and have been evaluated on different datasets with only one or two accuracy metrics. We systematically assessed 17 representative methods for drug response prediction on four large public datasets in nine metrics. In this talk, I will discuss a couple of methods that are among the best methods. I will also discuss the lessons obtained from this benchmarking study.